Biologist Dixit awarded $2M to study dynamics of intracellular scaffolds (Links to an external site)
Multi-tasking much, these days? The microtubule cytoskeleton is, too. Biologist Ram Dixit in Arts & Sciences at Washington University in St. Louis has been awarded $2 million by the National Institutes of Health to study this important shape-shifter.
Researchers uncover how cells interact with supporting proteins to heal wounds (Links to an external site)
Using 3D mapping, researchers uncover a process that has stymied mechanobiology
An ion channel senses cell swelling and helps cells to choose a response (Links to an external site)
Mechanosensitive channel transporting ions induces program of cell suicide
How to build better highways in plants (Links to an external site)
Dixit lab finds motor proteins that create more stable tracks to deliver much-needed materials
Collagen fibers encourage cell streaming by balancing individual aggression with collective cooperation (Links to an external site)
Amit Pathak found that collagen fiber length within the body may be a key overlooked parameter that some normal cells use to become invasive
International collaboration leads to cellular mechanobiology discovery (Links to an external site)
While engineers have gathered a lot of information about cells, they have not been able to tell the difference between how structural and material stiffnesses affect the behavior of a cell — until now.
In cells, more persistent leaders drive response of group (Links to an external site)
Cells in a group mimic birds migrating in a flock, giving insight into how aggressive tumor cells invade the body
Role of cell group behavior target of $1.9 million award (Links to an external site)
Mechanical engineer’s research on cell behavior’s relationship to metastasis gets boost from NIH grant
Defects in tissue trigger disease-like transformation of cells (Links to an external site)
Amit Pathak, assistant professor of mechanical engineering in the School of Engineering & Applied Science, and his team found that one small defect in tissue boundaries known as the basement membrane can lead normal cells to take on characteristics of diseased cells, such as cancer cells, and invade the surrounding tissue.
A partnership for well-being (Links to an external site)
Washington University and the National University of Singapore (NUS) partnered to present the multi-day symposia, “University Partnerships for Innovation: Advancing Human Well-Being.” The event included a symposium on mechanobiology, one on inclusion in asset building, and a special joint session on innovation partnerships. The aim was to illuminate applied research and innovations at the intersection of social policy, engineering and medicine.
Genin named inaugural Faught Professor of Mechanical Engineering (Links to an external site)
Guy Genin, an internationally renowned expert in mechanobiology, was installed as the Harold and Kathleen Faught Professor of Mechanical Engineering at Washington University in St. Louis Feb. 12.
Keeping plant-cell motors on track (Links to an external site)
Molecular brakemen keep transporter proteins in check until it’s their turn to move
Advancing well-being with global partnerships (Links to an external site)
Washington University in St. Louis strives to help solve some of the world’s biggest problems, but the effort doesn’t occur in a vacuum. The university is fully engaged with a global network of partners, via education programs and research initiatives, to develop tangible and lasting solutions.
Cells’ mechanical memory could hold clues to cancer metastasis (Links to an external site)
New use for a pesky weed (Links to an external site)
How dandelion seeds act as a perfect pipette in the lab