WashU researchers observe cancer-like nucleoli in healthy cells
McKelvey School of Engineering •
mage showing nucleolar bodies, with F-actin (red) and nucleolin (green), in human breast cancer cells (MDA-MB-231) cultured on soft (0.5 kPa) hydrogels. This study demonstrates changes in nucleolar composition in cells due to their tumorigenic potential and environmental cues. The image was acquired on a laser-scanning confocal microscope (ZEISS LSM 880) using a 63X objective. (Image: Florence Flick Jaecker, Department of Mechanical Engineering & Materials Science, Washington University in St. Louis)
